Could a headset using light and sound really help reverse Alzheimer’s? New data says yes.

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Aqualane Clinical Research

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Apr 25, 2025

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Florida - Southwest

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Cognito Therapeutics is gaining momentum—and $73 million in fresh funding—thanks to compelling new evidence that its neuromodulation therapy could be a game-changer for Alzheimer’s treatment.The company recently published an analysis of its phase 2 study in the Journal of Alzheimer’s Disease, and the findings are striking: Patients using Cognito’s headset daily for six months saw increases in brain white matter and slower myelin loss, compared to declines in both among placebo users.

 

The headset, which delivers synchronized gamma-frequency light and sound through connected glasses and headphones, is designed to stimulate brainwave activity that may help restore neural health. This non-invasive therapy aims to combat the brain changes at the root of Alzheimer’s—specifically the degeneration of white matter and the loss of myelin, which are crucial for cognitive function. “These white matter and myelin findings may have significant implications for early Alzheimer’s intervention,” said Dr. Ralph Kern, Cognito’s Chief Medical Officer. He emphasized the entorhinal cortex’s critical role in memory circuits and disease progression. CEO Brent Vaughan added that targeting these changes could help identify individuals at high risk and open doors to earlier, more effective treatment.

 

Cognito is gearing up to expand trials and move closer to potential regulatory approval, fueling new hope for millions living with Alzheimer’s. If you're a patient, caregiver, or provider interested in learning more, contact Aqualane Clinical Research today before enrollment closes.

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Keeping Seniors Safe: 7 Essential Home Modifications to Prevent Falls

In Delta, Montrose, and the surrounding Colorado area, many older adults are choosing to age in placeright in the comfort of their own homes. But with that decision comes an important responsibility: making sure their homes are as safe as possible. Falls are one of the leading causes of injury among seniors, and even a minor fall can have lasting consequences.1 in 4 adults age 65 and older falls each year in the United States.At Comfort Keepers of Delta and Montrose, CO, were committed to helping families create safe, supportive environments for their aging loved ones. In fact, we are a leading provider of in-home senior care services within the community and have helped many seniors navigate aging-in-place. Whether you're caring for a parent, spouse, or other senior loved one, these seven simple tips can go a long way toward preventing falls and giving everyone peace of mind. Clear the Clutter and Remove Tripping HazardsSometimes the biggest risks are the simplest to fix. Everyday items like area rugs, cords, or even a pet toy in the hallway can cause a serious fall. These hazards often go unnoticed because they're part of the daily routinebut for seniors, one misstep can lead to injury. Taking time to clear these obstacles can make a huge difference in their ability to safely age-in-place. Things to look for:     Loose rugs that could slip or bunch up      Electrical cords stretched across walkways      Narrow or cluttered hallways and furniture arrangements      Pet bowls or small items left on the floor      Frequently used items stored out of reach, leading to dangerous reaching or climbing      Slippery socks or shoes without proper tread Doing a room-by-room walk-through can be a great first step toward fall prevention. Make the Bathroom Safer for SeniorsBathrooms are one of the most common places for senior falls, especially with water and smooth surfaces involved. A few smart additions can make a big difference. Installing grab bars, using non-slip mats, and adding a shower chair can greatly improve safety and reduce the risk of slipping. Since so many daily routines happen in the bathroom, making it safer is one of the most impactful steps you can take.A few bathroom changes that can make the bathroom safer for seniors, include:     Grab bars near the toilet and in the shower or tub      A shower chair or bench for stability during bathing      Handheld showerheads for easier, safer bathing      Non-slip mats or adhesive strips on floors and in tubs 3. Rearrange Furniture for Safer MovementThe way a home is set up matters. If furniture blocks the flow of movement or is unstable, it increases the chance of a fall.Suggestions for a safer layout:     Keep walkways open and free of clutter      Choose chairs with arms and firm cushions for easier sitting and standing      Avoid furniture with sharp corners or glass surfaces      Adjust bed height to ensure it's easy to get in and out of Improve Lighting Throughout the HouseAs we age, it becomes harder to see clearly in dim or uneven lighting. Making sure the home is well-lit, especially in the evening, can help prevent missteps. Hallways, stairs, and bathrooms should be equipped with bright, accessible lighting to guide the way. Simple upgrades like night lights or motion-sensor bulbs can go a long way in helping seniors feel more confident moving aroundespecially when they wake up during the night. Tips for better visibility:     Swap out dim bulbs for brighter, more energy-efficient ones      Install night lights in bedrooms, bathrooms, and hallways      Add motion-sensor lights for nighttime trips to the bathroom      Make sure light switches are easy to access, particularly near entryways and bedsides At Comfort Keepers in Delta, CO, our professional in-home caregivers can help change light bulbs and do other light housekeeping tasks around a senior's home. Use Non-Slip Flooring SolutionsSome types of flooring, especially tile, hardwood, or linoleum, can be slippery underfoot. Tackling flooring issues can help seniors feel more confident as they move around. Adding non-slip mats, securing loose rugs, or applying anti-slip coatings are simple changes that make a big impact. Even small upgrades can reduce the chance of slips and create a steadier, safer surface for daily movement.Simple fixes include:     Applying non-slip coatings to hard surfaces      Using non-slip mats in places like the kitchen and bathroom      Removing or securing throw rugs to prevent bunching or curling edges      Avoiding thick or uneven rugs that could catch a foot or mobility aid Make Stairways Safer for Senior Navigating the HomeIf the home has stairs, its important to give them extra attention. One missed step can quickly lead to injury. Adding sturdy handrails on both sides, improving lighting, and using non-slip treads can make stairs much safer. For those with limited mobility, it may also be worth exploring options like ramps or stair lifts to reduce the risk of falls altogether.Helpful stair safety measures:     Add secure handrails on both sides of the stairs      Install bright lighting along staircases      Use contrast tape or tread strips to highlight steps      Consider adding a stair lift if stairs are frequently used and mobility is limited      For small thresholds or steps, ramps may be a better solution Create a Safer, More Accessible KitchenThe kitchen is a high-traffic area with a lot of activity, and plenty of opportunities for slips or strains.A few small updates can help:     Store everyday items within easy reach to avoid bending or climbing      Use pull-out drawers and turntables in cabinets      Set up a seated workspace for preparing meals     Add non-slip mats in front of the sink and stoveThese changes help reduce risks while allowing seniors to stay active, independent, and confident in their own homes. For more helpful advice, check out these additional kitchen safety tips for seniors on the Comfort Keepers corporate blog. Taking the First Step Toward Fall Prevention for Seniors in Delta, Montrose, and the Surrounding CO CommunitiesIf you're caring for an aging loved one in Delta or the surrounding area, remember that you dont have to make all these changes at once. Start by addressing the most noticeable safety concerns, then gradually add improvements over time. Including your loved one in the process not only helps them feel more comfortable with the changes but also empowers them to take an active role in their own safety. If you have immediate concerns, it may be time to explore senior care services as an option to help.  Comfort Keepers of Delta Is Here to HelpAt Comfort Keepers, we specialize in more than just in-home care, were focused on helping seniors live confidently and joyfully in their own homes. Our caregivers are trained to spot fall risks, support mobility, and provide companionship and assistance with daily tasks that can become more difficult with age.If youre ready to explore how Comfort Keepers of Delta and Montrose, CO can support your loved one through compassionate in-home senior care, were just a phone call away. Call Comfort Keepers of Delta today at 970-241-8818 or visit https://www.comfortkeepers.com/offices/colorado/delta-montrose/contact/contact-us/to schedule your free in-home consultation

Recognizing Memory Loss: 7 Early Signs a Parent May Need Support

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Emotional changes such as increased anxiety, signs of depression, or a tendency to isolate from others may be more than just a normal part of aging. These behavioral shifts are often among the earliest indicators of cognitive decline.What you can do: Begin by observing and documenting any patterns or changes in behavior. If these changes persist or seem out of character, it may be time to consult with a healthcare professional for further evaluation. Repeating Themselves OftenIf Mom is asking the same question several times in a short span or forgetting conversations entirely, it could indicate short-term memory loss.Tip: Try using calendars, written notes, or simple routines to support memory without causing frustration. Tracking how often this happens can help a doctor better assess the situation. Getting Lost in Familiar PlacesGetting turned around in a neighborhood theyve lived in for years or feeling disoriented in a regular grocery store is cause for concern.Safety comes first: Consider technology like GPS-enabled devices or check-in calls. Comfort Keepers caregivers can also provide reliable companionship and transportation around Grand Junction to help reduce stress and confusion. Making Poor or Risky DecisionsHave you noticed unexpected purchases, missed bills, or poor hygiene? These may be signs that your parents judgment is affected.Next steps: Offer to help with finances or mail in a supportive way. You might also consider speaking with an elder law professional about protections like a durable power of attorney. Difficulty with Daily RoutinesStruggling to cook meals, take medications correctly, or keep up with laundry may indicate its time for extra help. These routine activities, known as activities of daily living (ADLs), are essential to maintaining health and quality of life. When these tasks become challenging, it can put your loved one at risk for malnutrition, missed medications, or unsafe living conditions.How we can help: Comfort Keepers caregivers in Grand Junction can assist with everyday tasks while encouraging your parents independence and dignity. From preparing nutritious meals and organizing medications to light housekeeping and laundry, our compassionate team is here to provide reliable support, always with a focus on safety, respect, and preserving your loved ones sense of autonomy. Trouble Managing FinancesStacks of unpaid bills, late payments, or confusion over basic transactions might be signs your parent is struggling with memory-related issues.Your role: Offer to go over finances together, suggest automatic payments, or set reminders. If the issues persist, it might be time for more hands-on help or professional advice. Communication ChallengesAre they struggling to find the right words, follow conversations, or losing interest in talking altogether? While occasional communication lapses are common with age, consistent difficulty with communication may signal something more serious than typical senior moments. These changes can be early signs of cognitive decline and may lead to feelings of frustration, isolation, or withdrawal if not addressed.Offer support: Create a comfortable environment by speaking slowly, allowing extra time for responses, and encouraging conversation without pressure. Comfort Keepers caregivers are specially trained in compassionate, respectful communication techniques that help seniors feel heard and valued. 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Hurricane Preparedness Tips for Dementia Caregivers

Hurricane season is almost here. Now is the time to get your disaster plan ready. If you care for someone with Alzheimers or another type of dementia, its important to plan ahead to keep them safe.Here are some tips to help you prepare:      Shelters can be stressful for people with dementia. If you can, stay with friends or family. If you need to go to a special needs shelter, try to visit it before a storm to make sure it is a good fit.       Know the plan at any place your loved one visits or lives at, like a senior center or care home. Ask how they handle emergencies and who will help with evacuations.       Be ready for changes. People with dementia may get upset by changes in routine or being in a new place. They may wander or act out. Watch closely for signs of stress.       Stay together. Dont leave your loved one alone. Its easy for them to get lost, even in familiar places.       Stay calm. Your calm behavior can help them stay calm too.       Pack a kit. Include copies of important papers like legal documents, insurance cards, Social Security cards, a recent photo of your loved one, their doctors contact information, and the phone number for the Alzheimers Association Helpline (800-272-3900). To help caregivers, the Florida chapters of the Alzheimers Association teamed up with the University of South Florida. Together, they created a disaster preparedness guide for dementia caregivers with tips, shelter and evacuation info, and advice for talking with someone who has dementia.For more tips and local resources, visit alz.org or call the Alzheimers Association 24/7 Helpline at 800-272-3900. About the Alzheimers Association  The Alzheimers Association is a worldwide group that supports Alzheimers care, research and awareness. The groups mission is to end Alzheimers and all other dementias by leading global research, promoting early detection and risk reduction, and helping families. Its vision is a world without Alzheimers and all other dementia.

Local Services By This Author

Aqualane Clinical Research

Health Screenings 3200 Bailey Lane, Naples, Florida, 34105

HistoryWith a combined 50+ years of clinical research, Dr. Justiz, Dr. Baker, and Kelly Calistri founded Aqualane Clinical Research in 2022. Since 2005, Dr. Justiz and Dr. Baker have been conducting studies together as Principal Investigators for their private practice. With a shared vision for a larger research institute, Kelly, a long-time consultant to the doctors, joined them in forming Aqualane Clinical Research.Message FromOur FoundersAt Aqualane, we always put our patients first.We promise to educate each potential participant and their family members on all options available to them and to support them in their decision-making process. Striving to make clinical trials a practical healthcare option, we provide a comfortable, caring and compassionate environment.Our founders are passionate about their contributions to the advancement of medicine and to the opportunities they provide to people searching for new treatment options. With expertise and experience in research and the central nervous system, you can trust our team of neurologists and researchers to provide the best possible opportunity for you or your loved one.OurTeamDr. William A. Justiz, MDMedical Director, Principal InvestigatorDr. William Justiz completed his undergraduate degree at Northwestern University before receiving his medical degree from the University of Miami School of Medicine. He is board certified in neurology and is a certified physician investigator through the Association of Clinical Research Professionals.With over 20 years of research experience and specialization in degenerative diseases of the nervous system, he has been in continuous practice in Naples, Florida since 1999. He is a founding member of the clinical research program that has grown into Aqualane Clinical Research.Community outreach and service is one of the core values of Dr. Justiz and Aqualane Clinical Research. Dr. Justiz demonstrates this with his 23-year commitment to providing low-cost or free services to epilepsy patients through Epilepsy Services of Southwest Florida. In addition, he has delivered a free educational lecture series every month on all Alzheimer's topics since 2015 through the Alzheimer's Support network.Kelly E. Calistri, B.A.Chief Operating Officer, Site DirectorKelly is a native Floridian, born and raised in Central Florida. Shortly before graduating from The University of Tennessee, Knoxville, with a degree in Psychology, she was introduced to the research industry. Almost immediately, she knew this would be her career path.While working at a privately owned clinical research site in Atlanta, she gained experience in several areas, including patient intake, research coordinator, regulatory, and cognitive rater. Working for years across many therapeutic areas, her passion for research grew. With this experience, Kelly received promotions into management roles. Her responsibilities included conducting training, oversight of a staff of 50 people, managing Phase I studies in a unit with 40 beds, and being responsible for business development by attending industry meetings to represent her site. Before opening Aqualane Clinical Research in 2022, she used her expertise and experience to build two startup research sites. Building a team of experts who excel in their field is among her strongest qualities. Her passion for people and the advancement of medicine drives her daily to continue learning. Kelly has seen how new medications can change the lives of people around her.In her free time, you can find Kelly and her husband, who are high school sweethearts, at local baseball fields cheering on their two sons. They are a close family who loves to travel and spend time together. Kelly also loves reading business and personal development books.Dr. Matthew J. Baker, MDPrincipal InvestigatorDr. Baker is a board-certified neurologist practicing for over 20 years. He has been a Principal Investigator in numerous clinical trials, many of which have resulted in regulatory approval of novel therapeutics across the spectrum of neurologic disease, both here and abroad. His primary areas of interest include Neuroimmunology, migraine, and the Neurobehavioral manifestations of disease. Dr. Baker is a nationally recognized educator and lecturer. He enjoys teaching colleagues, medical residents and patients on such topics as Multiple Sclerosis and Myasthenia Gravis. In his spare time, he loves riding roller coasters with this family and playing with his two dogs.Micaela M. Acres, RN, BSNInfusion NurseJacqueline E. BradyCommunity Outreach Coordinator/ ReceptionMatthew B. Cagney, B.S.Clinical Research CoordinatorElena Capron, B.S.Regulatory Coordinator / Social Media CoordinatorBrittany N. Cordero, B.S.Office Manager / Human ResourcesJessica M. DEntremont, RN, MPH, BSNInfusion NurseDarious T. Davis, M.A.Head of Business DevelopmentLaura Gold, B.S.Finance CoordinatorKarma L. Hamilton, M.S.Lead RaterBethany J.M. Henchesmoore, MBAClinical Research CoordinatorJennifer Jimenez-Perez, RN, BSNInfusion NurseCarmen L. Ojeda, M.S.Quality Assurance / Quality ControlMichelle A. O'Neill, M.S.RaterMayve SantosResearch PharmacistAlexandria L. SmithClinical Research Coordinator

Aqualane Clinical Research

Clinical Studies 3200 Bailey Lane, Naples, Florida, 34105

About UsWith over 55 years of clinical research experience, Aqualane Clinical Research is committed to advancing medical science and improving lives. By leveraging our expertise in research, we dedicate ourselves to the community and the pursuit of innovative solutions for complex health challenges through the study of new medications.Our MissionWe strive to serve our community by providing cutting-edge experimental treatments for difficult-to-control and untreated neurological conditions. Through ethical, patient-centered research, we seek to develop breakthrough therapies that address unmet medical needs.What We DoAqualane Clinical Research is a leading clinical research organization specializing in the development of new treatments for a wide range of neurological and neuropsychiatric disorders. We collaborate closely with patients, caregivers, and industry sponsors to ensure the safe, ethical, and effective study of emerging therapies. Our goal is to offer hope and innovation where current treatments are limited or nonexistent.Our Commitment to Excellence50+ Years of Expertise Our experienced team of doctors and research professionals is dedicated to providing the highest level of care.100% Patient Satisfaction We are committed to guiding patients through the clinical trial process with compassion and transparency.Our Clinical Research AreasWe are actively conducting research in the following areas:Alzheimers Disease Investigating potential treatments to slow, halt, or reverse disease progression.Parkinsons Disease Developing therapies to improve quality of life and manage symptoms.Essential Tremor Exploring the genetic factors and treatment options for this movement disorder.Multiple Sclerosis Advancing treatments through biomarker analysis and cutting-edge imaging.Migraine Studying new medications to provide relief for those suffering from chronic migraine attacks.Neuropsychiatric Conditions Researching novel therapies for depression, anxiety, and psychiatric symptoms associated with neurological disorders.Get InvolvedDiscover how you can participate in a clinical study and contribute to the future of medical innovation. Our team is ready to answer any questions you may have.Meet the TeamDr. William A. Justiz, MDMedical Director, Principal InvestigatorDr. William Justiz completed his undergraduate degree at Northwestern University before receiving his medical degree from the University of Miami School of Medicine. He is board certified in neurology and is a certified physician investigator through the Association of Clinical Research Professionals.With over 20 years of research experience and specialization in degenerative diseases of the nervous system, he has been in continuous practice in Naples, Florida since 1999. He is a founding member of the clinical research program that has grown into Aqualane Clinical Research.Community outreach and service is one of the core values of Dr. Justiz and Aqualane Clinical Research. Dr. Justiz demonstrates this with his 23-year commitment to providing low-cost or free services to epilepsy patients through Epilepsy Services of Southwest Florida. In addition, he has delivered a free educational lecture series every month on all Alzheimer's topics since 2015 through the Alzheimer's Support network.Kelly E. Calistri, B.A.Chief Executive Officer, Site DirectorKelly is a native Floridian, born and raised in Central Florida. Shortly before graduating from The University of Tennessee, Knoxville, with a degree in Psychology, she was introduced to the research industry. Almost immediately, she knew this would be her career path.While working at a privately owned clinical research site in Atlanta, she gained experience in several areas, including patient intake, research coordinator, regulatory, and cognitive rater. Working for years across many therapeutic areas, her passion for research grew. With this experience, Kelly received promotions into management roles. Her responsibilities included conducting training, oversight of a staff of 50 people, managing Phase I studies in a unit with 40 beds, and being responsible for business development by attending industry meetings to represent her site. Before opening Aqualane Clinical Research in 2022, she used her expertise and experience to build two startup research sites. Building a team of experts who excel in their field is among her strongest qualities. Her passion for people and the advancement of medicine drives her daily to continue learning. Kelly has seen how new medications can change the lives of people around her.In her free time, you can find Kelly and her husband, who are high school sweethearts, at local baseball fields cheering on their two sons. They are a close family who loves to travel and spend time together. Kelly also loves reading business and personal development books.Dr. Matthew J. Baker, MDMedical Advisor, Principal InvestigatorDr. Baker is a board-certified neurologist practicing for over 20 years. He has been a Principal Investigator in numerous clinical trials, many of which have resulted in regulatory approval of novel therapeutics across the spectrum of neurologic disease, both here and abroad. His primary areas of interest include Neuroimmunology, migraine, and the Neurobehavioral manifestations of disease. Dr. Baker is a nationally recognized educator and lecturer. He enjoys teaching colleagues, medical residents and patients on such topics as Multiple Sclerosis and Myasthenia Gravis. In his spare time, he loves riding roller coasters with this family and playing with his two dogs.

Aqualane Clinical Research

Parkinsons Support & Research 3200 Bailey Lane, Naples, Florida, 34105

HistoryWith a combined 50+ years of clinical research, Dr. Justiz, Dr. Baker, and Kelly Calistri founded Aqualane Clinical Research in 2022. Since 2005, Dr. Justiz and Dr. Baker have been conducting studies together as Principal Investigators for their private practice. With a shared vision for a larger research institute, Kelly, a long-time consultant to the doctors, joined them in forming Aqualane Clinical Research.Message FromOur FoundersAt Aqualane, we always put our patients first.We promise to educate each potential participant and their family members on all options available to them and to support them in their decision-making process. Striving to make clinical trials a practical healthcare option, we provide a comfortable, caring and compassionate environment.Our founders are passionate about their contributions to the advancement of medicine and to the opportunities they provide to people searching for new treatment options. With expertise and experience in research and the central nervous system, you can trust our team of neurologists and researchers to provide the best possible opportunity for you or your loved one.OurTeamDr. William A. Justiz, MDMedical Director, Principal InvestigatorDr. William Justiz completed his undergraduate degree at Northwestern University before receiving his medical degree from the University of Miami School of Medicine. He is board certified in neurology and is a certified physician investigator through the Association of Clinical Research Professionals.With over 20 years of research experience and specialization in degenerative diseases of the nervous system, he has been in continuous practice in Naples, Florida since 1999. He is a founding member of the clinical research program that has grown into Aqualane Clinical Research.Community outreach and service is one of the core values of Dr. Justiz and Aqualane Clinical Research. Dr. Justiz demonstrates this with his 23-year commitment to providing low-cost or free services to epilepsy patients through Epilepsy Services of Southwest Florida. In addition, he has delivered a free educational lecture series every month on all Alzheimer's topics since 2015 through the Alzheimer's Support network.Kelly E. Calistri, B.A.Chief Operating Officer, Site DirectorKelly is a native Floridian, born and raised in Central Florida. Shortly before graduating from The University of Tennessee, Knoxville, with a degree in Psychology, she was introduced to the research industry. Almost immediately, she knew this would be her career path.While working at a privately owned clinical research site in Atlanta, she gained experience in several areas, including patient intake, research coordinator, regulatory, and cognitive rater. Working for years across many therapeutic areas, her passion for research grew. With this experience, Kelly received promotions into management roles. Her responsibilities included conducting training, oversight of a staff of 50 people, managing Phase I studies in a unit with 40 beds, and being responsible for business development by attending industry meetings to represent her site. Before opening Aqualane Clinical Research in 2022, she used her expertise and experience to build two startup research sites. Building a team of experts who excel in their field is among her strongest qualities. Her passion for people and the advancement of medicine drives her daily to continue learning. Kelly has seen how new medications can change the lives of people around her.In her free time, you can find Kelly and her husband, who are high school sweethearts, at local baseball fields cheering on their two sons. They are a close family who loves to travel and spend time together. Kelly also loves reading business and personal development books.Dr. Matthew J. Baker, MDPrincipal InvestigatorDr. Baker is a board-certified neurologist practicing for over 20 years. He has been a Principal Investigator in numerous clinical trials, many of which have resulted in regulatory approval of novel therapeutics across the spectrum of neurologic disease, both here and abroad. His primary areas of interest include Neuroimmunology, migraine, and the Neurobehavioral manifestations of disease. Dr. Baker is a nationally recognized educator and lecturer. He enjoys teaching colleagues, medical residents and patients on such topics as Multiple Sclerosis and Myasthenia Gravis. In his spare time, he loves riding roller coasters with this family and playing with his two dogs.Micaela M. Acres, RN, BSNInfusion NurseJacqueline E. BradyCommunity Outreach Coordinator/ ReceptionMatthew B. Cagney, B.S.Clinical Research CoordinatorElena Capron, B.S.Regulatory Coordinator / Social Media CoordinatorBrittany N. Cordero, B.S.Office Manager / Human ResourcesJessica M. DEntremont, RN, MPH, BSNInfusion NurseDarious T. Davis, M.A.Head of Business DevelopmentLaura Gold, B.S.Finance CoordinatorKarma L. Hamilton, M.S.Lead RaterBethany J.M. Henchesmoore, MBAClinical Research CoordinatorJennifer Jimenez-Perez, RN, BSNInfusion NurseCarmen L. Ojeda, M.S.Quality Assurance / Quality ControlMichelle A. O'Neill, M.S.RaterMayve SantosResearch PharmacistAlexandria L. SmithClinical Research Coordinator