The Success of Aducanumab in Treating Alzheimer's Disease

Author

Kathleen Warshawsky, BSN, RN

Posted on

Feb 06, 2023

Book/Edition

Non-Book Market , Texas - Dallas, Collin, SE Denton & Rockwall Counties

The Success of Aducanumab in Treating Alzheimer's Disease

Aducanumab is a medication that has received a lot of attention in recent years for its potential in treating Alzheimer's disease. Alzheimer's is a progressive neurological disorder that affects memory, thinking, and behavior, and there is currently no cure for the condition. Aducanumab is a type of drug called a monoclonal antibody, which works by targeting and removing sticky deposits of a protein called beta-amyloid that build up in the brains of individuals with Alzheimer's.

Aducanumab has shown promising results in treating Alzheimer's disease. It is a monoclonal antibody that targets beta-amyloid, a protein that accumulates in the brain and is associated with the development of Alzheimer's. The drug works by removing beta-amyloid from the brain, slowing the progression of the disease and potentially improving cognitive function.

In clinical trials, Aducanumab has been shown to reduce beta-amyloid levels in the brain and slow cognitive decline in patients with early Alzheimer's disease. The results of these trials have been highly promising and have led to the approval of Aducanumab by regulatory agencies in several countries.

One of the most significant findings of the clinical trials was the observation of a statistically significant reduction in clinical decline in patients who received Aducanumab. This reduction in decline was observed in measures of cognitive function, such as memory and thinking skills, as well as in measures of daily functioning, such as the ability to perform basic activities of daily living.

Another important finding from the trials was the observation of a favorable safety profile for Aducanumab. The majority of patients who received the medication did not experience significant side effects, and those that did were generally mild and manageable.

In November 2021, the United States Food and Drug Administration (FDA) granted accelerated approval for Aducanumab as a treatment for Alzheimer's disease. This decision was based on evidence from clinical trials, as well as on the need for new treatments for Alzheimer's, which is a growing global health crisis. The FDA has required the manufacturer of Aducanumab, Biogen, to conduct additional studies to confirm the drug's benefits and to better understand its risks and side effects.

The development of Aducanumab has been the subject of numerous clinical trials, with positive results seen in early trials in reducing beta-amyloid deposits in the brains of individuals with Alzheimer's. It is important to note however, that more recent trials have produced mixed results, with some studies showing a slowing of cognitive decline in individuals taking Aducanumab and others showing little to no effect.

Aducanumab is a promising new treatment option for Alzheimer's, although more research is needed to determine its long-term safety and effectiveness. Individuals and their families should discuss with their healthcare provider the potential benefits and risks of taking Aducanumab, as well as other treatment options that may be available.

In conclusion, Aducanumab is a medication that has received attention for its potential in treating Alzheimer's disease. The drug works by targeting and removing beta-amyloid deposits in the brain, which is believed to contribute to the progression of the disease. While the results of clinical trials have been mixed, the FDA has granted accelerated approval for Aducanumab as a treatment for Alzheimer's, with additional studies required to confirm its benefits and risks. Individuals and their families should consult with their healthcare provider to determine if Aducanumab is the right treatment option for them.

References:

·      Alzheimer's Association. (2021). Aducanumab.

·      Biogen. (2021). Aducanumab.

·      FDA. (2021). Aducanumab Approval Letter.

·      National Institute on Aging. (2021). Alzheimer's Disease and Dementia.

 

Author: Kathleen Warshawsky, BSN, RN | Publisher Seniors Blue Book Greater Dallas | https://www.linkedin.com/in/kathleenwbsnrn/

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Declutter with Joy: Preparing Senior Homes for a Peaceful Holiday Season

As the holiday season approaches, many families are excited about the festivities, gatherings, and the warmth that comes from celebrating with loved ones. However, for seniors, the holidays can sometimes evoke a different sentiment, especially when their homes are cluttered and overwhelming. At A Call to Order, we believe that decluttering not only creates a more organized space but also cultivates joy and comfort during this special time. In this blog, well discuss how decluttering can transform senior homes into serene sanctuaries, offering a few tips on how to embark on this rewarding journey.The Emotional Weight of ClutterIts no secret that clutter can induce feelings of stress and anxiety. For seniors, this burden can become significantly heavier. Aging can bring about physical limitations, mood fluctuations, and even feelings of loss or nostalgia. The accumulation of belongings, once cherished, can start to serve as a reminder of whats gone. The transition from cluttered environments to clean spaces not only visually uplifts homes but can also enhance emotional well-being. Decluttering before the holidays not only prepares a space for festivities but also creates an inviting environment for family gatherings. Imagine a peaceful home where your loved one can enjoy the laughter and joy of shared moments without the distraction of clutter. Thats the magic of creating a comfortable space. Tip 1: Embrace Memories, Let Go of ExcessWhen embarking on the decluttering journey, its essential to approach it with sensitivity and empathy. Start by setting aside time to sort through belongings, emphasizing the emotional significance of each piece. A great way to engage your loved one in this process is to invite them to share stories about the items theyve kept. This can be a wonderful bonding experience and can also help them to understand which items truly hold value for them. Actionable Steps:Create Categories: Designate separate areas for items to keep, donate, and discard.Use the One-Year Rule: If your loved one hasnt used or enjoyed an item in the past year, it may be time to let it go.Utilize Memory Boxes: Encourage them to keep a small box for particularly cherished items this helps preserve memories while still reducing clutter.Simplify Spaces for a Stress-Free HolidayOnce the tough decisions about what to keep have been made, its time to create a simplified living space thats easy to navigate and joyful to inhabit. A clean, organized home can significantly lighten the holiday load, allowing everyone to focus on what truly matters: creating memories with family. Tip 2: Optimize Storage and Layout for ComfortAfter decluttering, its essential to think about the layout of furniture and storage solutions. A well-organized, open space enhances movement and reduces hazards. Consider these steps to optimize their environment in a way that ensures safety and ease of access.Actionable Steps:Furniture Arrangement: Arrange furniture to facilitate conversation and movement. Create cozy corners for relaxation, ensuring pathways are clear.Accessible Storage Solutions: Use bins, baskets, or labels to store items neatly. Place frequently used items within easy reach to foster independence and comfort.Holiday Spirit Decor: Once the clutter is cleared, add some holiday touches. Whether its a simple wreath or a collection of family photos, personal touches can bring warmth and joy.The Emotional PayoffAs you embark on this journey of decluttering with your senior loved ones, remember that the emotional payoff can be profound. Clearing their homes of clutter can lead to renewed energy and enthusiasm for the holiday season, allowing them to focus on what truly matters family, love, and connection. A serene environment sets the stage for memorable family gatherings, enhancing the holidays in a deeply meaningful way.At A Call to Order, we are passionate about helping seniors create spaces that reflect joy and ease. Decluttering may initially seem like a daunting task, but with the right approacha sprinkle of love and patienceit can transform into a fulfilling experience. As we gear up for this joyful season, lets ensure that our senior loved ones feel comforted and treasured in their homes. With every item sorted, we pave the way for a warm and peaceful holiday season filled with laughter, love, and cherished moments. Lets celebrate the magic of the holidays by creating a home that invites joy! If you need assistance in your decluttering journey or would like a helping hand, dont hesitate to reach out. Together, we can embrace the spirit of the season while creating space for comfort and connection. Happy holidays from all of us at A Call to Order!

Lets talk PATHWAYS: Personalized Support for Those Experiencing Cognitive Decline

Lets talk PATHWAYS:  Personalized Support for Those Experiencing Cognitive DeclineDecember 5, 2024 By CC Young StaffThis time of year is filled with gatherings, which means you may be spending more quality time with your family members, particularly your parents and older relatives. While time spent together is a blessing, it can also highlight changes brought on by aging. If you believe someone you love is experiencing mild cognitive decline, there are options for keeping them safe while maintaining their independence and quality of life.This year, CC Young Senior Living in Dallas launched the Personal Assistance Toward Health and Wellness As You Succeed (PATHWAYS) program. Designed to serve as a bridge between Assisted Living and Memory Support, PATHWAYS provides extra support and structure in an intimate, small-group setting.We sat down with Nena Paris, CC Youngs Administrator, Assisted Living and Memory Support, to better understand the PATHWAYS program and who can benefit from it. Here are seven takeaways.PATHWAYS was created to fill a need between Assisted Living and Memory Support. The program came about because, often, Memory Support units can have long waitlists and fill up quickly. Truthfully, sometimes people with cognitive impairment dont necessarily need full Memory Support, as theyre not at risk of eloping, or leaving the community without supervision. CC Young has recognized that theres this middle group people who need a little more guided assistance and structure with their daily activities but are not qualified for full-blown Memory Support.PATHWAYS can actually slow cognitive decline. Research has shown that a guided program like PATHWAYS can in fact slow cognitive decline and help people stay engaged. Our program does this by providing residents with personal interaction, along with physical and emotional support, as a way to enhance their overall wellness and quality of life in a positive environment.PATHWAYS promotes resident wellness. At CC Young, we focus on whole-person wellness, using the 7 Pillars of Wellness as defined by the International Council on Active Aging: physical, social, spiritual, intellectual, emotional, vocational, and environmental wellness. Thats also the backbone of the PATHWAYS program, which promotes active aging regardless of cognitive issues. From these pillars, we have designed a comprehensive therapeutic program to support the needs of those with mild cognitive impairment in a joyful, engaging environment.PATHWAYS offers an intimate caregiver-to-resident ratio. Part of what makes PATHWAYS so successful is that the CC Young staff works closely with residents, which means the staff will notice any cognitive changes. In fact, at 1 caregiver to 7 people, the caregiver-to-resident ratio in PATHWAYS is better than both Assisted Living and Memory Support, which are 1 to 25 and 1 to 10, respectively. That also results in PATHWAYS residents becoming like family, as the staff truly gets to know them.PATHWAYS is not just for CC Young residents. Its true anyone from the Dallas community who has a need for the program can become a PATHWAYS resident. Upon entering the PATHWAYS program, your family member would also become an Assisted Living resident in The Hillside at CC Young.PATHWAYS is a less stressful transition for both family members and residents. It can certainly be stressful for families to face the decision of whether or not their family member should enter Memory Support. PATHWAYS offers a comforting solution for both them and their loved ones, as it lessens the pressure of deciding whether full Memory Support is needed now. The PATHWAYS resident may be able to live out their days in the PATHWAYS program or eventually transition to Memory Support, if the need arises.PATHWAYS keeps residents engaged and prevents isolation. To keep PATHWAYS residents engaged, the program takes an active and intentional approach to life enrichment activities, which includes participating in activities on the Assisted Living calendar as well as a specialized PATHWAYS calendar. The biggest differentiator for PATHWAYS is that a dedicated support staff member helps residents plan their day and escorts them to the activities. Since we purposely guide residents to keep them engaged, they are able to remain active and enjoy a better quality of life, while also avoiding any isolation that can be a symptom of cognitive decline.PATHWAYS is just one more service that CC Young offers current and prospective residents and their families. When we noticed an increase of older adults experiencing various levels of cognitive decline but not necessarily to the level of needing Memory Support we wanted to do something about it. We put our heads together and created a solution: PATHWAYS.If you are noticing cognitive decline in someone you love, we encourage you to have a conversation to express what youre observing. Talking to your primary care physician is a good place to start. CC Young is also happy to provide information, so feel free to give us a call at 214-305-9662.

Timeless Treasures: Keeping Memories Close to Heart

In a world filled with constant change and digital distractions, it can be easy to overlook one of lifes most meaningful aspects: our memories. Memories shape who we are, connecting us to significant people, places, and experiences that have enriched our lives. At A Call to Order Professional Organizer, we understand the importance of preserving these moments as timeless treasures. In this blog, we will explore the significance of keeping memories close to your heart and share practical tips to help you organize and cherish them effectively.The Value of Memories in Our LivesMemories are like a thread woven through the fabric of our lives, providing context and meaning to our existence. Heres why preserving memories is essential:Emotional ConnectionRoots of Identity: Our memories are a core part of our identity. They remind us of our experiences, journeys, and growth. By reflecting on our past, we understand ourselves better and connect with our roots.Nurturing Relationships: Memories often serve as the foundation of our relationships. Shared experiences create bonds that can foster connection and understanding between loved ones. Remembering milestones, laughter, and even challenges not only honors those moments but also strengthens our ties with others.Legacy and ReflectionCreating a Legacy: Preserving memories allows you to create a legacy for future generations. By documenting your experiences, stories, and values, you can pass down essentials that highlight what matters most to your family.Opportunity for Reflection: Taking time to reflect on your memories offers a sense of peace and nostalgia. It allows you to appreciate the journey youve taken and can serve as a reminder of the resilience and joy you possess.Tips for Preserving Timeless TreasuresWhile memories can sometimes feel ephemeral, there are numerous ways to keep them alive and accessible. Here are actionable tips to help you organize and honor your cherished moments:Step 1: Organize Physical KeepsakesCreate a Memory Box: Invest in a beautiful box or container where you can store physical keepsakes such as letters, postcards, photographs, and small mementos. Label each item with a date and a brief description to capture the essence of its significance.Sort and Curate: Regularly go through your collection to remove duplicates and items that no longer resonate with you. This curation helps maintain focus on the most meaningful treasures and keeps your collection manageable.Step 2: Digital DocumentationScan Important Documents and Photos: In today's digital age, its essential to preserve memories electronically. Use a scanner or a mobile scanning app to digitize important documents, photos, and keepsakes. This ensures that you have backups of your cherished items, even if the originals wear out or get lost.Create Digital Albums: Organize your digital photos into albums on your computer or cloud storage. You can create thematic collections (such as vacations, family gatherings, or milestones) to make them easily accessible. Regularly updating them can also spark joy as you take trips down memory lane.Step 3: Storytelling and JournalingStart a Memory Journal: Dedicate a journal to documenting your favorite memories, experiences, and reflections. You can write about significant events, feelings associated with certain moments, or stories passed down through generations. This practice provides an excellent outlet for self-expression and introspection.Share Family Stories: Consider scheduling regular family gathering times where you can share and document stories. Utilize voice recording apps to capture these moments with family and friends. These shared narratives create a deeper connection to your past and preserve family history for future generations.Step 4: Display Your MemoriesCreate a Memory Wall: Dedicate a wall or a section of your home to display photos, art, and keepsakes that tell your story. This not only showcases your memories but also invites conversations with guests who can appreciate your journey.Use Shadow Boxes: For three-dimensional treasures like souvenirs, awards, or delicate items from special events, consider using shadow boxes. This allows you to create beautiful and meaningful displays while protecting items from wear and tear.Step 5: Regularly Reflect and CelebrateCelebrate Milestones: Make it a tradition to celebrate anniversaries, birthdays, and other milestones where you can revisit cherished memories together. Create new traditions that involve sharing stories or looking through old photo albums, further enriching your memories.Schedule Regular Memory Check-ins: Take the time to reflect on your memories regularly. Whether its through quiet personal moments or gatherings with loved ones, revisiting memories can evoke warm feelings and gratitude, reinforcing their significance.Conclusion: Keep Your Memories Close to HeartAt A Call to Order Professional Organizer, we believe that memories are invaluable treasures that deserve to be cherished and preserved. By taking intentional steps to organize and celebrate your experiences, youll create a rich tapestry of memories that can provide comfort, joy, and connection throughout your life.As you embark on this journey of preserving your timeless treasures, remember that its not just about the items themselves; its about the stories, emotions, and relationships that shaped those moments. Embrace the art of memory-keeping and allow your cherished past to enrich your present and influence your future. If you ever feel overwhelmed with how to organize your keepsakes or create a meaningful memory-keeping system, A Call to Order is here to help you every step of the waybecause your memories are worth celebrating and keeping close to heart.

Local Services By This Author

Lifeline Screening

Medical & Wellness , , ,

Dont Let a Stroke Ruin Your RetirementYour risk of stroke and cardiovascular disease increases as you age. But the good news is 80% of stroke and cardiovascular disease CAN be prevented.1 If you are age 50 or older, you should be screened.Often there arent any symptoms of a stroke before it occurs, in fact for 4 out of 5 people who have a stroke the first symptom of any illness is the actual stroke.2 But, you can take steps to find out if youre at risk.Life Line Screening is a premier provider of preventive screenings for stroke and cardiovascular disease risk. A simple appointment can identify your risk factors and provide peace of mind or early detection.Screenings are easy, painless, non-invasive and dont require any messy prep work.Life Line Screening has over 14,000 locations across the United States so you can find one close to you.Getting screened is affordable. The most popular package at Life Line Screening includes 5 screenings in 1 appointment for $149.Get the most out of your life! Find out your stroke and cardiovascular disease risk with Life Line Screening so you can be in control and do something about it.***CLICK HERE*** to schedule your appointment! A simple screening can be worth a lifetime.1 American Heart Association https://www.heart.org/en/get-involved/advocate/federal-priorities/cdc-prevention-programs2 Hackam DG, Karpral MK, et al. Most stroke patients do not get a warning, a Population Based Cohort Study. Sept. 2009. Neurology, 73, 1074-1075.

STAP (Specialized Telephone Assistive Program)

Hearing/Deaf Products , , Texas,

If You Have A Hearing, Vision Or Mobility Problems Accessing Or Using A Telephone - You May Qualify For A Free Telephone! 4 out of 5 Americans over the age of 60 have some hearing, vision or mobility loss. There is help however and it is paid for by you through a government program called STAP, Specialized Telecommunications Assistance Program, by a small charge each month on your telephone bill. Why not take advantage of a benefit youre paying for already? Contact Laura Carr, STAP to learn more about this program and show you what equipment youre eligible to receive FREE OF CHARGE! To qualify, you must be a Texas resident with a problem with vision, hearing or mobility. You are entitled to one FREE phone every 5 years. You can get a cell phone, landline, smartphone or tablet, depending on your disability. Must provide proof of residency. Acceptable forms of residency include:*  Texas Drivers License*   ID card with address*   Voters Registration card*   Letter from facility on their stationery*   Utility Bill (current - showing address)*   Vehicle registration card*   Medicaid ID*   Medicare Summary This program is for any Texas Resident that has a Vision, Hearing, Mobility- including cognitive problems.  They are entitled to FREE telephone equipment (just the device) and they have to pay their monthly charges to their telephone service provider.  Depending on their impairment, they may qualifiy for a Landline Telephone with a medical alert system; a Regular Cell Phone (where they can make calls, text, take photos including a medical alert button on the back.  If they have a hearing problem, they can receive a 2-way texting device - an Android Smart Phone or Android Tablet.  They have to provide their proof of residency for the State of Texas:  a current drivers license, Texas ID, Voters Registration Card or a Utility bill showing their name & current address & date.   Laura can assist with completing an application, take a photo of their proof of residency - attach to their signed application & send it to STAP headquarters in Austin, Texas.  The State processes their application & mails the Voucher for the equipment, directly to the Resident.  Once they receive the Voucher, they contact Laura and she will deliver the equipment that is authorized on the voucher to the Resident.  NO MONEY CHANGES HANDS. Laura Carr, STAP Specialist has worked with this program for 16 years.Contact Laura at 214-388-0088 or LauraCarr@prodigy.net