Alzheon’s Alzheimer’s Trial Shows Promising Results – We’re Honored to Be Part of It
Aqualane Clinical Research
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Apr 02, 2025
Florida - Southwest
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Alzheon has reported encouraging results from its Phase 2 trial of ALZ-801, an oral treatment for early Alzheimer’s disease. The study showed cognitive benefits, a 28% reduction in hippocampal atrophy, and a strong safety profile, particularly for individuals with two copies of the APOE4 gene.
With the Phase 3 trial now fully enrolled, topline results are expected in the near future. If successful, ALZ-801 could become the first oral anti-amyloid therapy for high-risk patients.
Aqualane is proud to be part of this groundbreaking research and extend our deepest gratitude to all participants whose contributions are shaping the future of Alzheimer’s treatment.
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Naples Clinic Expands to Provide Free Medications for Low-Income Workers
For low-income Collier County residents who are working but uninsured, access to the medications they need is not as easy as going to a regular chain pharmacy to pick them up. Thats where the Neighborhood Health Clinics expanded non-narcotic medication room comes in, giving patients managing chronic conditions including hypertension and diabetes timely access to medications at no cost. The 1,850-square-foot medication room, located at the clinic on Goodlette-Frank Road near Central Avenue, was built at a cost of $500,000 and is named for the late Stacy Forman, a Naples philanthropist who donated funding for the expansion.Keith Maples, CEO of Neighborhood Health Clinic, said the expanded medications facility enhances the clinics ability to serve patients faster and more efficiently. On a typical day, a patient can walk in and when they walk out, theyre walking out with thousands of dollars worth of medication that, if it were outside of the Clinic, they would not be able to fill those prescriptions because it would be outside of what they could afford, Maples said. He said the expanded space, equipped with updated technology and increased storage capacity, allows for a larger inventory of non-narcotic medications that enables the Clinic to fill prescriptions immediately to minimize delays in treatment. In 2024, the Clinic distributed $6.5 million in retail value of medications thanks to partnerships with Americares, Direct Relief, Dispensary of Hope and other pharmaceutical companies. The expansion allows us to work even more with our pharmaceutical partners to basically procure all of the medications necessary for our patients, Maples said. He said that many patients arriving at the Clinic for the first time have not previously received medical care for the condition needing treatment and may have vastly elevated blood pressure or blood sugar levels, for example. When they walk through the doors, theyre at such a heightened level that were trying to bring it back to a controlled number to where its manageable for them, Maples said. If their A1Cs are through the roof, their [blood] sugars are through the roof, were trying to get them back to an established number that helps them feel better. Well never cure them of all those illnesses, but well maintain that health for them, so they feel better and have a better quality of life.Clinic grows to meet patient demand The nonprofit Neighborhood Health Clinic was established in 1999 by Dr. Bill and Nancy Lascheid to provide medical care to low-income, working but uninsured Collier County adults. Their daughter, Leslie Lascheid, now serves as president of the organization. In 2024 the clinic saw more than 12,000 patient visits and delivered more than 30,000 patient procedures, Maples said, with all medications, primary care, specialty care, surgeries and outpatient procedures provided free of charge to patients.All funding is through philanthropy, as the Clinic does not receive any city, county, state or federal funding including Medicaid or Medicare. Over the years the clinic has expanded as the patient load has increased. The original 11,000-square-foot facility more than doubled in size with the completion of the Armstrong Medical Specialties Building in 2021, which expanded the campus to 23,000 square feet. The addition of the Van Domelen Education and Wellness Building, also in 2021, took the total to its current 32,000 square feet, and when the Bill and Candy Raveis Pathology Building is completed this summer, the total campus will be at 43,000 square feet, according to Marcie Berland, the Clinics director of development. 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When that patient walks through the doors, I never want them to wonder where theyre going to get their care or how theyre getting to their next appointment, Maples said. Many of our patients get rides here, or they walk or ride their bikes, because very few own cars that they can drive in. And while the Clinic does have a full-time paid staff of 14 and five part-time staff, no medical professionals are paid to deliver care, Maples said. More than 250 physicians, 50 dentists, 100 nurses and 300 non-medical personnel deliver care and provide patient education on a volunteer basis.
Beyond the Surface: Naples Cancer Advisors Spotlight Melanoma During Awareness Month
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Aqualane Clinical Research
Memory Screening 3200 Bailey Lane, Naples, Florida, 34105HistoryWith a combined 50+ years of clinical research, Dr. Justiz, Dr. Baker, and Kelly Calistri founded Aqualane Clinical Research in 2022. Since 2005, Dr. Justiz and Dr. Baker have been conducting studies together as Principal Investigators for their private practice. With a shared vision for a larger research institute, Kelly, a long-time consultant to the doctors, joined them in forming Aqualane Clinical Research.Message FromOur FoundersAt Aqualane, we always put our patients first.We promise to educate each potential participant and their family members on all options available to them and to support them in their decision-making process. 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He is board certified in neurology and is a certified physician investigator through the Association of Clinical Research Professionals.With over 20 years of research experience and specialization in degenerative diseases of the nervous system, he has been in continuous practice in Naples, Florida since 1999. He is a founding member of the clinical research program that has grown into Aqualane Clinical Research.Community outreach and service is one of the core values of Dr. Justiz and Aqualane Clinical Research. Dr. Justiz demonstrates this with his 23-year commitment to providing low-cost or free services to epilepsy patients through Epilepsy Services of Southwest Florida. In addition, he has delivered a free educational lecture series every month on all Alzheimer's topics since 2015 through the Alzheimer's Support network.Kelly E. Calistri, B.A.Chief Operating Officer, Site DirectorKelly is a native Floridian, born and raised in Central Florida. Shortly before graduating from The University of Tennessee, Knoxville, with a degree in Psychology, she was introduced to the research industry. Almost immediately, she knew this would be her career path.While working at a privately owned clinical research site in Atlanta, she gained experience in several areas, including patient intake, research coordinator, regulatory, and cognitive rater. Working for years across many therapeutic areas, her passion for research grew. With this experience, Kelly received promotions into management roles. Her responsibilities included conducting training, oversight of a staff of 50 people, managing Phase I studies in a unit with 40 beds, and being responsible for business development by attending industry meetings to represent her site. Before opening Aqualane Clinical Research in 2022, she used her expertise and experience to build two startup research sites. Building a team of experts who excel in their field is among her strongest qualities. Her passion for people and the advancement of medicine drives her daily to continue learning. Kelly has seen how new medications can change the lives of people around her.In her free time, you can find Kelly and her husband, who are high school sweethearts, at local baseball fields cheering on their two sons. They are a close family who loves to travel and spend time together. Kelly also loves reading business and personal development books.Dr. Matthew J. Baker, MDPrincipal InvestigatorDr. Baker is a board-certified neurologist practicing for over 20 years. He has been a Principal Investigator in numerous clinical trials, many of which have resulted in regulatory approval of novel therapeutics across the spectrum of neurologic disease, both here and abroad. His primary areas of interest include Neuroimmunology, migraine, and the Neurobehavioral manifestations of disease. Dr. Baker is a nationally recognized educator and lecturer. He enjoys teaching colleagues, medical residents and patients on such topics as Multiple Sclerosis and Myasthenia Gravis. In his spare time, he loves riding roller coasters with this family and playing with his two dogs.Micaela M. Acres, RN, BSNInfusion NurseJacqueline E. BradyCommunity Outreach Coordinator/ ReceptionMatthew B. Cagney, B.S.Clinical Research CoordinatorElena Capron, B.S.Regulatory Coordinator / Social Media CoordinatorBrittany N. Cordero, B.S.Office Manager / Human ResourcesJessica M. DEntremont, RN, MPH, BSNInfusion NurseDarious T. Davis, M.A.Head of Business DevelopmentLaura Gold, B.S.Finance CoordinatorKarma L. Hamilton, M.S.Lead RaterBethany J.M. Henchesmoore, MBAClinical Research CoordinatorJennifer Jimenez-Perez, RN, BSNInfusion NurseCarmen L. Ojeda, M.S.Quality Assurance / Quality ControlMichelle A. O'Neill, M.S.RaterMayve SantosResearch PharmacistAlexandria L. SmithClinical Research Coordinator
Aqualane Clinical Research
Clinical Studies 3200 Bailey Lane, Naples, Florida, 34105About UsWith over 55 years of clinical research experience, Aqualane Clinical Research is committed to advancing medical science and improving lives. By leveraging our expertise in research, we dedicate ourselves to the community and the pursuit of innovative solutions for complex health challenges through the study of new medications.Our MissionWe strive to serve our community by providing cutting-edge experimental treatments for difficult-to-control and untreated neurological conditions. Through ethical, patient-centered research, we seek to develop breakthrough therapies that address unmet medical needs.What We DoAqualane Clinical Research is a leading clinical research organization specializing in the development of new treatments for a wide range of neurological and neuropsychiatric disorders. We collaborate closely with patients, caregivers, and industry sponsors to ensure the safe, ethical, and effective study of emerging therapies. Our goal is to offer hope and innovation where current treatments are limited or nonexistent.Our Commitment to Excellence50+ Years of Expertise Our experienced team of doctors and research professionals is dedicated to providing the highest level of care.100% Patient Satisfaction We are committed to guiding patients through the clinical trial process with compassion and transparency.Our Clinical Research AreasWe are actively conducting research in the following areas:Alzheimers Disease Investigating potential treatments to slow, halt, or reverse disease progression.Parkinsons Disease Developing therapies to improve quality of life and manage symptoms.Essential Tremor Exploring the genetic factors and treatment options for this movement disorder.Multiple Sclerosis Advancing treatments through biomarker analysis and cutting-edge imaging.Migraine Studying new medications to provide relief for those suffering from chronic migraine attacks.Neuropsychiatric Conditions Researching novel therapies for depression, anxiety, and psychiatric symptoms associated with neurological disorders.Get InvolvedDiscover how you can participate in a clinical study and contribute to the future of medical innovation. Our team is ready to answer any questions you may have.Meet the TeamDr. William A. Justiz, MDMedical Director, Principal InvestigatorDr. William Justiz completed his undergraduate degree at Northwestern University before receiving his medical degree from the University of Miami School of Medicine. He is board certified in neurology and is a certified physician investigator through the Association of Clinical Research Professionals.With over 20 years of research experience and specialization in degenerative diseases of the nervous system, he has been in continuous practice in Naples, Florida since 1999. He is a founding member of the clinical research program that has grown into Aqualane Clinical Research.Community outreach and service is one of the core values of Dr. Justiz and Aqualane Clinical Research. Dr. Justiz demonstrates this with his 23-year commitment to providing low-cost or free services to epilepsy patients through Epilepsy Services of Southwest Florida. In addition, he has delivered a free educational lecture series every month on all Alzheimer's topics since 2015 through the Alzheimer's Support network.Kelly E. Calistri, B.A.Chief Executive Officer, Site DirectorKelly is a native Floridian, born and raised in Central Florida. Shortly before graduating from The University of Tennessee, Knoxville, with a degree in Psychology, she was introduced to the research industry. Almost immediately, she knew this would be her career path.While working at a privately owned clinical research site in Atlanta, she gained experience in several areas, including patient intake, research coordinator, regulatory, and cognitive rater. Working for years across many therapeutic areas, her passion for research grew. With this experience, Kelly received promotions into management roles. Her responsibilities included conducting training, oversight of a staff of 50 people, managing Phase I studies in a unit with 40 beds, and being responsible for business development by attending industry meetings to represent her site. Before opening Aqualane Clinical Research in 2022, she used her expertise and experience to build two startup research sites. Building a team of experts who excel in their field is among her strongest qualities. Her passion for people and the advancement of medicine drives her daily to continue learning. Kelly has seen how new medications can change the lives of people around her.In her free time, you can find Kelly and her husband, who are high school sweethearts, at local baseball fields cheering on their two sons. They are a close family who loves to travel and spend time together. Kelly also loves reading business and personal development books.Dr. Matthew J. Baker, MDMedical Advisor, Principal InvestigatorDr. Baker is a board-certified neurologist practicing for over 20 years. He has been a Principal Investigator in numerous clinical trials, many of which have resulted in regulatory approval of novel therapeutics across the spectrum of neurologic disease, both here and abroad. His primary areas of interest include Neuroimmunology, migraine, and the Neurobehavioral manifestations of disease. Dr. Baker is a nationally recognized educator and lecturer. He enjoys teaching colleagues, medical residents and patients on such topics as Multiple Sclerosis and Myasthenia Gravis. In his spare time, he loves riding roller coasters with this family and playing with his two dogs.
Aqualane Clinical Research
Parkinsons Support & Research 3200 Bailey Lane, Naples, Florida, 34105HistoryWith a combined 50+ years of clinical research, Dr. Justiz, Dr. Baker, and Kelly Calistri founded Aqualane Clinical Research in 2022. Since 2005, Dr. Justiz and Dr. Baker have been conducting studies together as Principal Investigators for their private practice. With a shared vision for a larger research institute, Kelly, a long-time consultant to the doctors, joined them in forming Aqualane Clinical Research.Message FromOur FoundersAt Aqualane, we always put our patients first.We promise to educate each potential participant and their family members on all options available to them and to support them in their decision-making process. Striving to make clinical trials a practical healthcare option, we provide a comfortable, caring and compassionate environment.Our founders are passionate about their contributions to the advancement of medicine and to the opportunities they provide to people searching for new treatment options. With expertise and experience in research and the central nervous system, you can trust our team of neurologists and researchers to provide the best possible opportunity for you or your loved one.OurTeamDr. William A. Justiz, MDMedical Director, Principal InvestigatorDr. William Justiz completed his undergraduate degree at Northwestern University before receiving his medical degree from the University of Miami School of Medicine. He is board certified in neurology and is a certified physician investigator through the Association of Clinical Research Professionals.With over 20 years of research experience and specialization in degenerative diseases of the nervous system, he has been in continuous practice in Naples, Florida since 1999. He is a founding member of the clinical research program that has grown into Aqualane Clinical Research.Community outreach and service is one of the core values of Dr. Justiz and Aqualane Clinical Research. Dr. Justiz demonstrates this with his 23-year commitment to providing low-cost or free services to epilepsy patients through Epilepsy Services of Southwest Florida. In addition, he has delivered a free educational lecture series every month on all Alzheimer's topics since 2015 through the Alzheimer's Support network.Kelly E. Calistri, B.A.Chief Operating Officer, Site DirectorKelly is a native Floridian, born and raised in Central Florida. Shortly before graduating from The University of Tennessee, Knoxville, with a degree in Psychology, she was introduced to the research industry. Almost immediately, she knew this would be her career path.While working at a privately owned clinical research site in Atlanta, she gained experience in several areas, including patient intake, research coordinator, regulatory, and cognitive rater. Working for years across many therapeutic areas, her passion for research grew. With this experience, Kelly received promotions into management roles. Her responsibilities included conducting training, oversight of a staff of 50 people, managing Phase I studies in a unit with 40 beds, and being responsible for business development by attending industry meetings to represent her site. Before opening Aqualane Clinical Research in 2022, she used her expertise and experience to build two startup research sites. Building a team of experts who excel in their field is among her strongest qualities. Her passion for people and the advancement of medicine drives her daily to continue learning. Kelly has seen how new medications can change the lives of people around her.In her free time, you can find Kelly and her husband, who are high school sweethearts, at local baseball fields cheering on their two sons. They are a close family who loves to travel and spend time together. Kelly also loves reading business and personal development books.Dr. Matthew J. Baker, MDPrincipal InvestigatorDr. Baker is a board-certified neurologist practicing for over 20 years. He has been a Principal Investigator in numerous clinical trials, many of which have resulted in regulatory approval of novel therapeutics across the spectrum of neurologic disease, both here and abroad. His primary areas of interest include Neuroimmunology, migraine, and the Neurobehavioral manifestations of disease. Dr. Baker is a nationally recognized educator and lecturer. He enjoys teaching colleagues, medical residents and patients on such topics as Multiple Sclerosis and Myasthenia Gravis. In his spare time, he loves riding roller coasters with this family and playing with his two dogs.Micaela M. Acres, RN, BSNInfusion NurseJacqueline E. BradyCommunity Outreach Coordinator/ ReceptionMatthew B. Cagney, B.S.Clinical Research CoordinatorElena Capron, B.S.Regulatory Coordinator / Social Media CoordinatorBrittany N. Cordero, B.S.Office Manager / Human ResourcesJessica M. DEntremont, RN, MPH, BSNInfusion NurseDarious T. Davis, M.A.Head of Business DevelopmentLaura Gold, B.S.Finance CoordinatorKarma L. Hamilton, M.S.Lead RaterBethany J.M. Henchesmoore, MBAClinical Research CoordinatorJennifer Jimenez-Perez, RN, BSNInfusion NurseCarmen L. Ojeda, M.S.Quality Assurance / Quality ControlMichelle A. O'Neill, M.S.RaterMayve SantosResearch PharmacistAlexandria L. SmithClinical Research Coordinator